An overview of the
Natural Capsaicinoids are a series of analogs. There are 19 known analogs, all of which share a common structure. They were first extracted from chili peppers in 1876 by Thresh, for their spicy flavor. It has functions of analgesia, anticancer, regulating blood fat, anti-bacterial and anti-inflammatory, weight loss, anti-fatigue, analgesia, antipruritic, anti-inflammatory, antioxidant, myocardial protection and blood pressure regulation, etc. It can also lead to skin blood vessel dilation, improve microcirculation, and produce a series of physiological reactions and repellent effects on humans and animals with its irritating and spicy taste. Therefore, it has a wide range of applications, mainly used in medical, cosmetic, biological control, food additives, military and other fields.
Pharmacological effects
Capsaicin has the following functions: 1. Analgesic effect; 2. Cardiovascular protective effect; Anticancer effect; 3. 4. Effects on the digestive system; 5. Antipruritus effect; 6. Antibacterial and insecticidal effects.
The physical and chemical properties
Capsaicin, the nature of the kind of material is very similar with capsaicin, capsaicin is tasted a flake or needle colorless crystalline monoclinic rectangle, melting point 65 ℃, boiling point of 210-220 ℃, soluble in ethanol, ethyl ether, acetone, benzene, and chloroform and other organic solvent and hot water and dilute alkali solution, slightly soluble in carbon disulfide, hardly soluble in cold water, capsaicin is a class of stable chemical properties, minimal loss in various organic solvent extraction process, it will produce irritating steam at high temperature.
In an alkali solution, thalidomide is hydrolyzed to vanillin amine and decanoic acid in small amounts. Easy to crystalline in ether, petroleum ether. Capsaicin is weakly acidic because of its light phenolic group and can react with Philin reagent.
Because the nitrogen atoms in the capsaicin molecules exist in the form of phthalamide bonds, the alkalinity almost disappears and cannot react with the acid. Low concentration capsaicin often forms a purple oil solution with pigment, glycoside and phospholipid.