Best price Capsaicin Capsaicin 404-86-4 in stock CAS NO.404-86-4

Min.Order: 1 Kilogram
Payment Terms: L/C,T/T,Other

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Best price Capsaicin
Capsaicin 404-86-4 in stock
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ProName: Best price Capsaicin Capsaicin 404-86-...
CasNo: 404-86-4
Molecular Formula: C15H22O2
Appearance: Light yellow to white crystal powder
Application: Plant extract
DeliveryTime: in stock
PackAge: 1 kg/bag,or according to the requireme...
Port: Shanghai,Qingdao or others
ProductionCapacity: 2000 Metric Ton/Year
Purity: 99%
Storage: Keep undercool, dry and well ventilate...
Transportation: by sea or by air
LimitNum: 1 Kilogram
Related Substances: refer to COA
Residue on Ignition: 3-5 YEARS

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Best price Capsaicin Capsaicin 404-86-4 in stock

Pharmacological effects

1. Prevention of cardiovascular Diseases When low-densitylipoprotein (LDL) is oxidized, the oxidized LOW-density lipoprotein (LDL) is produced and blocks the arteries, leading to atherosclerosis. Capsaicin is a potential antioxidant. Capsaicin is an effective vascular dilatation and diuretic for salt-induced hypertension model mice, maintaining normal blood pressure by balancing the nervous and hormonal systems. Calcitoningene-relatedpeptide (CGRP) is a peptide released from capsaicin-sensitive sensory nerve endings and is closely related to cardiovascular disease, especially hypertension.

2. The afferent nerve sensitive to capsaicin plays an important role in the defense mechanism of gastric mucosa in the prevention and treatment of digestive tract diseases. Capsaicin can stimulate the afferent nerve and increase the release of CGRP and Substance P in the stomach to protect the gastric mucosa. The sensory nerve of capsaicin plays an important role in the mucosal defense mechanism through the regulation of gastric functions such as mucosal blood flow and gastric peristalsis, which not only plays a protective role in the injury of gastric mucosa, but also contributes to the recovery of the injury. Capsaicin can stimulate oral mucosa to increase salivary amylase secretion, reflexively increase gastric movement, improve the activity of digestive enzymes, and improve digestive function.

3. Effects on respiratory diseases Nasal obstruction occurs when people are exposed to 0.5 to 1.0 PPM of chlorine gas for 15 minutes without a gas mask. Rats also had a direct nasal obstruction response similar to that of humans. Pretreatment with capsaicin could significantly reduce the rat's irritable sensation and nasal obstruction response to chlorine gas.

4. The effect of analgesic capsaicin on sensory nerves shows that topical application of capsaicin can desensitizes the body to pain and itch without affecting the mechanical stimulation threshold, such as temperature, pressure or tactile stimulation. Capsaicin can be a typical analgesic for the treatment of different pain conditions, which can relieve and improve patients' pain that cannot be controlled by other methods or with little or no control.

5. Anticancer capsaicin can change the expression of tumor genes. Capsaicin can inhibit the lipid peroxidation of aflatoxin B1 to the liver so as to reduce the damage of aflatoxin B1 to the liver. Capsaicin is effective in the treatment of human hepatoma. Capsaicin has an anti-prostate cancer effect in men and is expected to become an alternative to chemicals used to treat prostate cancer.

Capsaicin can promote lipid metabolism, dissolve fat, and inhibit fat accumulation in the body. Capsaicin into the human body, can promote the neurotransmitter acetylcholine and norepinephrine secretion, and adrenalin through sweating, burning fat can play a more effective role in weight loss.

7. For chilblains and baldness, capsaicin can dilate blood vessels, promote microcirculation and hair growth.

Prurigo is a general term for a group of acute or chronic inflammatory skin diseases. It usually occurs in the itching skin of the extension side of the limbs. The mechanism of its initiation is still unclear, and most of them are believed to be related to allergic reactions. Capsaicin stimulates the nerve to release CGRP and SP, which can effectively treat neurocutaneous inflammation and urticaria. Capsaicin can enhance the spontaneous discharge of renal transmission fibers. Capsaicin in adult females have removed uterus compensatory hypertrophy (compensatoryovarianhypertrophy, COH) ovary and compensating the therapeutic effect of ovulation (compensatoryovulation, CO). Capsaicin acts as a Chemicalbook inhibitor for many bacteria, it also inhibits fungi, is safer than chemical preservatives, and has nutritional benefits. Pepper is a kind of natural preservative with broad spectrum of bacteriostatic, and it has the characteristics of health, green and environmental protection. Hemp pepper has a good anti - fatigue effect.

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Analysis method

The main qualitative analysis methods are TLC, IR and UV. In addition, NUCLEAR magnetic resonance (NMR), nuclear magnetic resonance (NMR) and mass spectrometry (MS) are often used to identify the structures of capsaicin and distinguish their homoloids. The commonly used quantitative analysis methods include Kjeldahl method, FAO ultraviolet double colorimetric method, key blue colorimetric method and key sodium acid-sodium nitrite colorimetric method. The chilliness index of each homology of capsaicin has a big difference. However, the above methods can only measure the overall composition of capsaicin and cannot quantify the major chilli substances respectively. Therefore, the chilli and its products cannot be quantitatively analyzed and evaluated more accurately. The above information about natural capsaicin's pharmaceutical profile, physical and chemical properties, pharmacological action, plant morphology, etc., has been edited by Ding.

use

1. Biological control

A. The rat repellent with capsaicin as the main component of green grain storage had good repellent effect on the rats in rural grain storage. The repellent containing 1% capsaicin could keep the repellent effect for more than 5 months.

B. The stimulation of capsaicin for protection of cable and cable will have a repellent effect on animals. It can be used as a functional additive for anti-rat cable sheath plastic in the cable and cable industry; When used in PVC, PE and other plastics, it can prevent rats and termites from damaging the products by eating. Antifouling coatings biological antifouling coatings made from the repellent properties of capsaicin can be applied to the parts of ships and Marine buildings in contact with seawater, which can effectively prevent the attachment of Marine organisms and the aggregation of aquatic organisms on ship hulls. At present, capsaicin has replaced organic tin as a new antifouling paint for ships and Marine buildings. D. Capsaicin, a biological pesticide, can be used as a new green pesticide in the field of biological pesticides. It has good effects of contact killing and repellent, and can achieve the characteristics of high efficacy, long efficacy and degradation in crop pest control, and is a new environmental biological pesticide.

2. Medical cosmetology A. Medical capsaicin has significant effects on neuropathic pain, rheumatoid arthritis, fresh cowhide, psoriasis, acne, baldness and so on. Analgesia is one of the most mature applications in capsaicin research. Capsaicin can also be used in the prevention and treatment of cardiovascular and cerebrovascular diseases, in addition, capsaicin can also prevent and treat peptic ulcer and respiratory diseases, and has a special effect of weight loss, anti-fatigue and auxiliary drug addiction. B. Cosmetology can be used as raw materials for the production of cosmetic skincare products for the improvement of the skin quality of the face and arms, but different parts should pay attention to the difference in concentration.

3. Other areas

A. military capsaicin has good tear effect, can cause human body strong physiological response, make the person produces symptoms such as cough, vomiting, tears, or even lost, but non-toxic side effects, so the military made tear gas, and tear gun and defense weapon of main raw materials, in the United States, Japan, Germany and southeast Asia and other countries have been widely used. Capsaicin is also used as a personal defense weapon and as a tool to subdue lawbreakers.

B. Food additives can be used in the processing of all kinds of spicy food in food workers, including all kinds of spicy fat food, daily seasoning, spicy sauce, baked food, etc. In addition, capsaicin has strong antibacterial and bactericidal properties, and has certain inhibitory effects on bacteria, fungi and yeast, so it can be used as a potential food preservative.